Exogenus Therapeutics is thrilled to announce the granting of a new patent in the United States, marking a major milestone in the company’s global expansion. This is the second region to recognize the patent family titled: “Compositions comprising small extracellular vesicles derived from umbilical cord blood mononuclear cells with anti-inflammatory and immunomodulatory properties and process for obtaining them.” The same patent family has already been granted in Japan. This innovative technology harnesses Extracellular Vesicles naturally released by umbilical cord blood cells, pre-conditioned in a specific environment, to deliver a novel therapeutic approach for regenerative medicine. Through extensive research, Exogenus has fully characterized these exosomes and their bioactivity, revealing a multifactorial mode of action characterized by an anti-inflammatory and immunomodulatory effect that sets the foundation for next-generation regenerative therapies. Exogenus has also evolved the methods to produce and purify the Extracellular Vesicles with these properties, and which can be utilized for production of Extracellular Vesicles-based products in GMP conditions. Joana Simões Correia, CEO and inventor of the patent, commented: “Securing this U.S. patent is a significant achievement for Exogenus Therapeutics. It strengthens our intellectual property portfolio, opens doors to a robust international market, and reinforces our commitment to pioneering innovation in...

We are pleased to announce that Exogenus Therapeutics has been granted another patent, now in Europe! This is the fifth region to recognize the patent family titled “Use of umbilical cord blood-derived exosomes for tissue repair.” This patent family has also been granted in Canada, China, Japan and Korea. This invention leverages exosomes naturally released by umbilical cord blood cells, subjected to a specific pre-conditioning environment, and provides a therapeutic approach for regenerative medicine. Exogenus has thoroughly characterized these exosomes and their bioactivity, uncovering a multifactorial mechanism of action. Our CEO, Joana Correia, also inventor of the patent, stated: “This new European patent is a significant achievement for Exogenus Therapeutics. It opens doors to a robust international market, strengthens our patent portfolio, and highlights our commitment to innovation.” Exogenus Therapeutics' patent portfolio includes three families related to its lead product, Exo-101, covering different aspects of its composition, manufacturing process, and therapeutic applications (including inflammatory and fibrotic diseases). As a leading exosome biotech company, Exogenus is dedicated to developing innovative, safe, and effective therapies for patients with significant unmet needs. The company now plans to broaden the applications of its proprietary exosomes to treat a diverse range of conditions involving tissue...