patents & licenses

Click here WO/2017/163132

Use of Umbilical Cord Blood-Derived Exosomes for Tissue Repair

 

Granted

Granted

Under Evaluation

Granted

Granted

Granted

Click here WO/2020/070700

Compositions Comprising Small Extracellular Vesicles Derived from Umbilical Cord Blood Mononuclear Cells with Anti-Inflammatory and Immunomodulatory Properties

 

Under Evaluation

Granted

Under Evaluation

Click here WO2024105629

Use of Compositions Comprising Small EV Derived from Umbilical Cord Blood Mononuclear Cells with Anti-Inflammatory and Immunomodulatory Properties for Application to Fibrotic Lesions

 

disseminations

Exogenus Therapeutics is committed to giving back to the scientific community, by sharing what we learn along the way. Aside from accepting trainees and PhD students, Exogenus cultivates a culture of publishing in peer-reviewed journals. Additionally, our staff regularly contributes to conferences, often at the invite of the organizers.

SCIENTIFIC PUBLICATIONS:

Paolini et al., Large-scale production of extracellular vesicles: Report on the “massivEVs” ISEV workshop. J Extracell Biol. 2022; 1(10):e63. doi: 10.1002/jex2.63.

Link to publication

Rodrigues SC, Cardoso RMS, Freire PC, Gomes CF, Duarte FV, Neves RPD, SimõesCorreia J. Immunomodulatory Properties of Umbilical Cord Blood-Derived Small Extracellular Vesicles and Their Therapeutic Potential for Inflammatory Skin DisordersInt J Mol Sci.2021; 22(18):9797. doi: 10.3390/ijms22189797.

Link to publication

 

Rodrigues SC, Cardoso RMS, Gomes CF, Duarte FV, Freire PC, Neves R, Simoes-Correia J. Toxicological Profile of Umbilical Cord Blood-Derived Small Extracellular Vesicles. Membranes. 2021; 11(9):647. doi: 10.3390/membranes11090647.

Link to publication

 

Cardoso RMS, Rodrigues SC, Gomes CF, Duarte FV, Romao M, Leal EC, Freire PC, Neves R, Correia JS. Development of an optimized and scalable method for isolation of umbilical cord blood-derived small extracellular vesicles for future clinical use. STEM CELLS Transl Med. 2021; 1-12. doi: 10.1002/sctm.20-0376

Link to publication

Théry et al., Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 2018; 7(1):1535750. doi: 10.1080/20013078.2018.1535750.

Link to publication

SELECTED INVITED TALKS:

Correia, J. Extracellular Vesicles in Human Health: Opportunities and Challenges. Exosomes Europe, 2023, Jun 6; London, UK

 

Correia, J. Pre-clinical Development of Exosome-Based Therapeutics: Challenges, Barriers & Opportunities. 2nd Exosome Based Therapeutic Development Summit, 2020, Nov 12; Virtual

 

Correia, J. Therapeutic potential of UCB-derived extracellular vesicles. World Advanced Therapies and Regenerative Medicine Congress, 2019, May 17; London, UK

 

Correia, J. Umbilical Cord Blood supply for the development of Exo-Wound, an exosome-based product for Chronic Wounds. World Cord Blood Europe, 2017, May 17; London, UK

POSTERS:

Rodrigues, S. Development of a Standardized Exosomes Production Process for Clinical Use. International Society for Extracellular Vesicles (ISEV) Meeting, 2018, May 2-6; Barcelona, Spain

Link to the poster

 

Rodrigues, S. The Impact of Automatizing Umbilical Cord Blood Processing in the Production of an Exosome-Based Medicinal Product. 1st Vesicular Biology Meeting, 2018, 16-17; Coimbra, Portugal

Link to the poster