patents & licenses
Click here WO/2017/163132
Use of Umbilical Cord Blood-Derived Exosomes for Tissue Repair
Granted
Granted
Under Evaluation
Granted
Granted
Granted
Click here WO/2020/070700
Compositions Comprising Small Extracellular Vesicles Derived from Umbilical Cord Blood Mononuclear Cells with Anti-Inflammatory and Immunomodulatory Properties
Under Evaluation
Granted
Under Evaluation
Click here WO2024105629
Use of Compositions Comprising Small EV Derived from Umbilical Cord Blood Mononuclear Cells with Anti-Inflammatory and Immunomodulatory Properties for Application to Fibrotic Lesions
disseminations
Exogenus Therapeutics is committed to giving back to the scientific community, by sharing what we learn along the way. Aside from accepting trainees and PhD students, Exogenus cultivates a culture of publishing in peer-reviewed journals. Additionally, our staff regularly contributes to conferences, often at the invite of the organizers.
SCIENTIFIC PUBLICATIONS:
Paolini et al., Large-scale production of extracellular vesicles: Report on the “massivEVs” ISEV workshop. J Extracell Biol. 2022; 1(10):e63. doi: 10.1002/jex2.63.
Rodrigues SC, Cardoso RMS, Freire PC, Gomes CF, Duarte FV, Neves RPD, Simões–Correia J. Immunomodulatory Properties of Umbilical Cord Blood-Derived Small Extracellular Vesicles and Their Therapeutic Potential for Inflammatory Skin Disorders. Int J Mol Sci.2021; 22(18):9797. doi: 10.3390/ijms22189797.
Rodrigues SC, Cardoso RMS, Gomes CF, Duarte FV, Freire PC, Neves R, Simoes-Correia J. Toxicological Profile of Umbilical Cord Blood-Derived Small Extracellular Vesicles. Membranes. 2021; 11(9):647. doi: 10.3390/membranes11090647.
Cardoso RMS, Rodrigues SC, Gomes CF, Duarte FV, Romao M, Leal EC, Freire PC, Neves R, Correia JS. Development of an optimized and scalable method for isolation of umbilical cord blood-derived small extracellular vesicles for future clinical use. STEM CELLS Transl Med. 2021; 1-12. doi: 10.1002/sctm.20-0376
Théry et al., Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 2018; 7(1):1535750. doi: 10.1080/20013078.2018.1535750.
SELECTED INVITED TALKS:
Correia, J. Extracellular Vesicles in Human Health: Opportunities and Challenges. Exosomes Europe, 2023, Jun 6; London, UK
Correia, J. Pre-clinical Development of Exosome-Based Therapeutics: Challenges, Barriers & Opportunities. 2nd Exosome Based Therapeutic Development Summit, 2020, Nov 12; Virtual
Correia, J. Therapeutic potential of UCB-derived extracellular vesicles. World Advanced Therapies and Regenerative Medicine Congress, 2019, May 17; London, UK
Correia, J. Umbilical Cord Blood supply for the development of Exo-Wound, an exosome-based product for Chronic Wounds. World Cord Blood Europe, 2017, May 17; London, UK
POSTERS:
Rodrigues, S. Development of a Standardized Exosomes Production Process for Clinical Use. International Society for Extracellular Vesicles (ISEV) Meeting, 2018, May 2-6; Barcelona, Spain
Rodrigues, S. The Impact of Automatizing Umbilical Cord Blood Processing in the Production of an Exosome-Based Medicinal Product. 1st Vesicular Biology Meeting, 2018, 16-17; Coimbra, Portugal